Type I Interferon Production Enhances Susceptibility to Listeria monocytogenes Infection

Numerous bacterial products such as lipopolysaccharide potently induce type I interferons (IFNs); however, the contribution of this innate response to host defense against bacterial infection remains unclear. Although mice deficient in either IFN regulatory factor (IRF)3 or the type I IFN receptor (...

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Bibliographic Details
Main Authors: O'Connell, Ryan M., Saha, Supriya K., Vaidya, Sagar A., Bruhn, Kevin W., Miranda, Gustavo A., Zarnegar, Brian, Perry, Andrea K., Nguyen, Bidong O., Lane, Timothy F., Taniguchi, Tadatsugu, Miller, Jeff F., Cheng, Genhong
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211937/