Helicobacter pylori Modulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN

Helicobacter pylori Modulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN

The human gastric pathogen Helicobacter pylori spontaneously switches lipopolysaccharide (LPS) Lewis (Le) antigens on and off (phase-variable expression), but the biological significance of this is unclear. Here, we report that Le+ H. pylori variants are able to bind to the C-type lectin DC-SIGN and...

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Bibliographic Details
Main Authors: Bergman, Mathijs P., Engering, Anneke, Smits, Hermelijn H., van Vliet, Sandra J., van Bodegraven, Ad A., Wirth, Hans-Peter, Kapsenberg, Martien L., Vandenbroucke-Grauls, Christina M.J.E., van Kooyk, Yvette, Appelmelk, Ben J.
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211851/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211851/

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