B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue

Primary Sjögren's syndrome (pSS) is an autoimmune disorder characterized by specific pathological features. A hallmark of pSS is B-cell hyperactivity as manifested by the production of autoantibodies, hypergammaglobulinemia, formation of ectopic lymphoid structures within the inflamed tissues,...

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Bibliographic Details
Main Authors: Hansen, Arne, Lipsky, Peter E, Dörner, Thomas
Format: Online
Language:English
Published: BioMed Central 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206371/