Expression of nitric oxide synthase isoforms in the dorsal horn of monoarthritic rats: effects of competitive and uncompetitive N-methyl-D-aspartate antagonists
Chronic pain is associated with N-methyl-D-aspartate (NMDA) receptor activation and downstream production of nitric oxide, which has a pivotal role in multisynaptic local circuit nociceptive processing in the spinal cord. The formation of nitric oxide is catalyzed by three major nitric oxide synthas...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2007
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206346/ |