Equilibrium and Kinetic Properties of the Interaction between Tetrodotoxin and the Excitable Membrane of the Squid Giant Axon

Squid giant axons were treated with tetrodotoxin (TTX) in concentrations ranging from 1 nM to 25 nM and the resulting decrease in sodium current was followed in time using the voltage clamp technique. The removal of TTX from the bathing solution produced only partial recovery of the sodium current....

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Bibliographic Details
Main Authors: Cuervo, Leon Andres, Adelman, William J.
Format: Online
Language:English
Published: The Rockefeller University Press 1970
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203005/