Molecular Aspects of Polyene- and Sterol-Dependent Pore Formation in Thin Lipid Membranes

Amphotericin B modifies the permeability properties of thin lipid membranes formed from solutions containing sheep red cell phospholipids and cholesterol. At 10-6 M amphotericin B, the DC membrane resistance fell from ≈108 to ≈102 ohm-cm2, and the membranes became Cl--, rather than Na+-selective; t...

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Bibliographic Details
Main Authors: Dennis, Vincent W., Stead, Nancy W., Andreoli, Thomas E.
Format: Online
Language:English
Published: The Rockefeller University Press 1970
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203000/