Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump

Endocytosed proteins are sorted in early endosomes to be recycled to the plasma membrane or transported further into the degradative pathway. We studied the role of endosomes acidification on the endocytic trafficking of the transferrin receptor (TfR) as a representative for the recycling pathway, t...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1995
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199957/