Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148

Confluent endothelial cells respond poorly to the proliferative signals of VEGF. Comparing isogenic endothelial cells differing for vascular endothelial cadherin (VE-cadherin) expression only, we found that the presence of this protein attenuates VEGF-induced VEGF receptor (VEGFR) 2 phosphorylation...

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Bibliographic Details
Main Authors: Lampugnani, Maria Grazia, Zanetti, Adriana, Corada, Monica, Takahashi, Takamune, Balconi, Giovanna, Breviario, Ferruccio, Orsenigo, Fabrizio, Cattelino, Anna, Kemler, Rolf, Daniel, Thomas O., Dejana, Elisabetta
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199373/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199373/

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