Keratin 8 protection of placental barrier function

The intermediate filament protein keratin 8 (K8) is critical for the development of most mouse embryos beyond midgestation. We find that 68% of K8−/− embryos, in a sensitive genetic background, are rescued from placental bleeding and subsequent death by cellular complementation with wild-type tetrap...

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Bibliographic Details
Main Authors: Jaquemar, Daniel, Kupriyanov, Sergey, Wankell, Miriam, Avis, Jacqueline, Benirschke, Kurt, Baribault, Hélène, Oshima, Robert G.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199358/