Keratin 8 protection of placental barrier function
The intermediate filament protein keratin 8 (K8) is critical for the development of most mouse embryos beyond midgestation. We find that 68% of K8−/− embryos, in a sensitive genetic background, are rescued from placental bleeding and subsequent death by cellular complementation with wild-type tetrap...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2003
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199358/ |