An Acidic Motif Retains Vesicular Monoamine Transporter 2 on Large Dense Core Vesicles

The release of biogenic amines from large dense core vesicles (LDCVs) depends on localization of the vesicular monoamine transporter VMAT2 to LDCVs. We now find that a cluster of acidic residues including two serines phosphorylated by casein kinase 2 is required for the localization of VMAT2 to LDCV...

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Bibliographic Details
Main Authors: Waites, Clarissa L., Mehta, Anand, Tan, Philip K., Thomas, Gary, Edwards, Robert H., Krantz, David E.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199206/