Role of Different T Cell Receptors in the Development of Pre–T Cells

The development of pre–T cells with productive TCR-β rearrangements can be mediated by each the pre–T cell receptor (pre-TCR), the TCR-αβ as well as the TCR-γδ, albeit by distinct mechanisms. Although the TCR-γδ affects CD4−8− precursor cells irrespective of their rearrangement status by TCR-β mecha...

Full description

Bibliographic Details
Main Authors: Buer, Jan, Aifantis, Iannis, DiSanto, James P., Fehling, Hans Joerg, von Boehmer, Harald
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196301/