Lineage Relationships and Differentiation of Natural Killer (NK) T Cells: Intrathymic Selection and Interleukin (IL)-4 Production in the Absence of NKR-P1 and Ly49 Molecules

In this report, we have assessed the lineage relationships and cytokine dependency of natural killer (NK) T cells compared with mainstream TCR-αβ T cells and NK cells. For this purpose, we studied common γ chain (γc)-deficient mice, which demonstrate a selective defect in CD3− NK cell development re...

Full description

Bibliographic Details
Main Authors: Lantz, Olivier, Sharara, Lama I., Tilloy, Florence, Andersson, Åsa, DiSanto, James P.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196284/