The Human Immunodeficiency Virus Type 1 (HIV-1) Vpu Protein Interferes with an Early Step in the Biosynthesis of Major Histocompatibility Complex (MHC) Class I Molecules
The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a small integral membrane phosphoprotein with two established functions: degradation of the viral coreceptor CD4 in the endoplasmic reticulum (ER) and augmentation of virus particle release from the plasma membrane of HIV-1–infected ce...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1997
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196253/ |