Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire

Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire

Immature thymocytes undergo a selection process within the thymus based on their T cell antigen receptor (TCR) specificity that results either in their maturation into functionally competent, self-MHC–restricted T cells (positive selection) or their deletion (negative selection). The outcome of thym...

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Bibliographic Details
Main Authors: Shores, Elizabeth W., Tran, Tom, Grinberg, Alexander, Sommers, Connie L., Shen, Howard, Love, Paul E.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196173/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196173/

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