The Immunodominant Antigen of an Ultraviolet-induced Regressor Tumor Is Generated by a Somatic Point Mutation in the DEAD Box Helicase p68

The Immunodominant Antigen of an Ultraviolet-induced Regressor Tumor Is Generated by a Somatic Point Mutation in the DEAD Box Helicase p68

The genetic origins of CD8+ T cell–recognized unique antigens to which mice respond when immunized with syngeneic tumor cells are unknown. The ultraviolet light-induced murine tumor 8101 expresses an H-2Kb-restricted immunodominant antigen, A, that induces cytolytic CD8+ T cells in vivo A+ 8101 cell...

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Bibliographic Details
Main Authors: Dubey, Purnima, Hendrickson, Ronald C., Meredith, Stephen C., Siegel, Christopher T., Shabanowitz, Jeffrey, Skipper, Jonathan C.A., Engelhard, Victor H., Hunt, Donald F., Schreiber, Hans
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196148/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196148/

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