Inflammatory Chemokine Transport and Presentation in HEV: A Remote Control Mechanism for Monocyte Recruitment to Lymph Nodes in Inflamed Tissues

Interstitial fluid is constantly drained into lymph nodes (LNs) via afferent lymph vessels. This conduit enables monocyte-derived macrophages and dendritic cells to access LNs from peripheral tissues. We show that during inflammation in the skin, a second recruitment pathway is evoked that recruits...

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Bibliographic Details
Main Authors: Palframan, Roger T., Jung, Steffen, Cheng, Guiying, Weninger, Wolfgang, Luo, Yi, Dorf, Martin, Littman, Dan R., Rollins, Barrett J., Zweerink, Hans, Rot, Antal, von Andrian, Ulrich H.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195988/