Sensory Adaptation in Naive Peripheral CD4 T Cells

T cell receptor interactions with peptide/major histocompatibility complex (pMHC) ligands control the selection of T cells in the thymus as well as their homeostasis in peripheral lymphoid organs. Here we show that pMHC contact modulates the expression of CD5 by naive CD4 T cells in a process that r...

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Bibliographic Details
Main Authors: Smith, Katy, Seddon, Benedict, Purbhoo, Marco A., Zamoyska, Rose, Fisher, Amanda G., Merkenschlager, Matthias
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195983/