Novel Cell Type–Specific Antiviral Mechanism of Interferon γ Action in Macrophages

Interferon (IFN)-γ and macrophages (Mϕ) play key roles in acute, persistent, and latent murine cytomegalovirus (MCMV) infection. IFN-γ mechanisms were compared in embryonic fibroblasts (MEFs) and bone marrow Mϕ (BMMϕ). IFN-γ inhibited MCMV replication in a signal transducer and activator of transcri...

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Bibliographic Details
Main Authors: Presti, Rachel M., Popkin, Daniel L., Connick, Megan, Paetzold, Susanne, Virgin, Herbert W.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195910/