Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

C57BL/6 mice genetically deficient in interleukin 15 (IL-15−/− mice) were generated by gene targeting. IL-15−/− mice displayed marked reductions in numbers of thymic and peripheral natural killer (NK) T cells, memory phenotype CD8+ T cells, and distinct subpopulations of intestinal intraepithelial l...

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Bibliographic Details
Main Authors: Kennedy, Mary K., Glaccum, Moira, Brown, Sandra N., Butz, Eric A., Viney, Joanne L., Embers, Monica, Matsuki, Naoto, Charrier, Keith, Sedger, Lisa, Willis, Cynthia R., Brasel, Kenneth, Morrissey, Philip J., Stocking, Kim, Schuh, JoAnn C. L., Joyce, Sebastian, Peschon, Jacques J.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195858/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195858/

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