The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase

The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase

The great majority of patients that are intolerant of wheat gluten protein due to celiac disease (CD) are human histocompatibility leukocyte antigen (HLA)-DQ2+, and the remaining few normally express HLA-DQ8. These two class II molecules are chiefly responsible for the presentation of gluten peptide...

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Bibliographic Details
Main Authors: Arentz-Hansen, Helene, Körner, Roman, Molberg, Øyvind, Quarsten, Hanne, Vader, Willemijn, Kooy, Yvonne M.C., Lundin, Knut E.A., Koning, Frits, Roepstorff, Peter, Sollid, Ludvig M., McAdam, Stephen N.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195837/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195837/

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