Sulfation of a High Endothelial Venule–Expressed Ligand for L-Selectin: Effects on Tethering and Rolling of Lymphocytes

During lymphocyte homing, L-selectin mediates the tethering and rolling of lymphocytes on high endothelial venules (HEVs) in secondary lymphoid organs. The L-selectin ligands on HEV are a set of mucin-like glycoproteins, for which glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) is a cand...

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Bibliographic Details
Main Authors: Tangemann, Kirsten, Bistrup, Annette, Hemmerich, Stefan, Rosen, Steven D.
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195654/