Absence of Epithelial Immunoglobulin a Transport, with Increased Mucosal Leakiness, in Polymeric Immunoglobulin Receptor/Secretory Component–Deficient Mice

Absence of Epithelial Immunoglobulin a Transport, with Increased Mucosal Leakiness, in Polymeric Immunoglobulin Receptor/Secretory Component–Deficient Mice

Mucosal surfaces are protected specifically by secretory immunoglobulin A (SIgA) and SIgM generated through external translocation of locally produced dimeric IgA and pentameric IgM. Their active transport is mediated by the epithelial polymeric Ig receptor (pIgR), also called the transmembrane secr...

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Bibliographic Details
Main Authors: Johansen, Finn-Eirik, Pekna, Marcela, Norderhaug, Inger Natvig, Haneberg, Bjørn, Hietala, Max Albert, Krajci, Peter, Betsholtz, Christer, Brandtzaeg, Per
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195652/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195652/

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