Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts
In this study, we use primary embryonic fibroblasts derived from cyclooxygenase-deficient transgenic embryos to further investigate the role of the two cyclooxygenases, cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), in the process of neoplastic transformation. Cells with either, neither, or...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1999
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195603/ |