DNA-dependent Protein Kinase Activity Is Not Required for Immunoglobulin Class Switching

DNA-dependent Protein Kinase Activity Is Not Required for Immunoglobulin Class Switching

Class switch recombination (CSR), similar to V(D)J recombination, is thought to involve DNA double strand breaks and repair by the nonhomologous end–joining pathway. A key component of this pathway is DNA-dependent protein kinase (DNA-PK), consisting of a catalytic subunit (DNA-PKcs) and a DNA-bindi...

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Bibliographic Details
Main Authors: Bosma, Gayle C., Kim, Jiyoon, Urich, Teresa, Fath, Donna M., Cotticelli, Maria G., Ruetsch, Norman R., Radic, Marko Z., Bosma, Melvin J.
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194268/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194268/

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