LIME: A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling

Lymphocyte membrane rafts contain molecules critical for immunoreceptor signaling. Here, we report identification of a new raft-associated adaptor protein LIME (Lck-interacting molecule) expressed predominantly in T lymphocytes. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or...

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Bibliographic Details
Main Authors: Brdičková, Naděžda, Brdička, Tomáš, Angelisová, Pavla, Horváth, Ondrej, Špička, Jiří, Hilgert, Ivan, Pačes, Jan, Simeoni, Luca, Kliche, Stefanie, Merten, Camilla, Schraven, Burkhart, Hořejší, Václav
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194115/