Differential Antigen Presentation Regulates the Changing Patterns of CD8+ T Cell Immunodominance in Primary and Secondary Influenza Virus Infections

Differential Antigen Presentation Regulates the Changing Patterns of CD8+ T Cell Immunodominance in Primary and Secondary Influenza Virus Infections

The specificity of CD8+ T cell responses can vary dramatically between primary and secondary infections. For example, NP366–374/Db- and PA224–233/Db-specific CD8+ T cells respond in approximately equal numbers to a primary influenza virus infection in C57BL/6 mice, whereas NP366–374/Db-specific CD8+...

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Bibliographic Details
Main Authors: Crowe, Sherry R., Turner, Stephen J., Miller, Shannon C., Roberts, Alan D., Rappolo, Rachel A., Doherty, Peter C., Ely, Kenneth H., Woodland, David L.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194086/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194086/

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