Cross-linking the B7 Family Molecule B7-DC Directly Activates Immune Functions of Dendritic Cells

Cross-linking the B7 Family Molecule B7-DC Directly Activates Immune Functions of Dendritic Cells

B7-DC molecules are known to function as ligands on antigen-presenting cells (APCs), enhancing T cell activation. In this study, cross-linking B7-DC with the monoclonal antibody sHIgM12 directly potentiates dendritic cell (DC) function by enhancing DC presentation of major histocompatibility complex...

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Bibliographic Details
Main Authors: Nguyen, Loc T., Radhakrishnan, Suresh, Ciric, Bogoljub, Tamada, Koji, Shin, Tahiro, Pardoll, Drew M., Chen, Lieping, Rodriguez, Moses, Pease, Larry R.
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193990/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193990/

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