The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo
Lymphoproliferative (lpr) mice, which lack functional Fas receptor expression and develop autoimmune lymphoproliferative disease, have an accumulation of T cell receptor-αβ+CD4−CD8− (double negative T cells [DNTC]) in the periphery. The function of the accumulating DNTC is not clear. In this study w...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2002
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193928/ |