The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

Lymphoproliferative (lpr) mice, which lack functional Fas receptor expression and develop autoimmune lymphoproliferative disease, have an accumulation of T cell receptor-αβ+CD4−CD8− (double negative T cells [DNTC]) in the periphery. The function of the accumulating DNTC is not clear. In this study w...

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Bibliographic Details
Main Authors: Ford, Megan S., Young, Kevin J., Zhang, Zhuxu, Ohashi, Pamela S., Zhang, Li
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193928/