Regulation and Function of the Interleukin 13 Receptor α 2 During a T Helper Cell Type 2–dominant Immune Response

Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms that down-regulate these reactions. Interleukin (IL)-13 has emerged as a central mediator of T helper cell (Th)2-...

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Bibliographic Details
Main Authors: Chiaramonte, Monica G., Mentink-Kane, Margaret, Jacobson, Bruce A., Cheever, Allen W., Whitters, Matthew J., Goad, Mary E.P., Wong, Anthony, Collins, Mary, Donaldson, Debra D., Grusby, Michael J., Wynn, Thomas A.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193852/