Activation of Dendritic Cells through the Interleukin 1 Receptor 1 Is Critical for the Induction of Autoimmune Myocarditis

Activation of Dendritic Cells through the Interleukin 1 Receptor 1 Is Critical for the Induction of Autoimmune Myocarditis

Dilated cardiomyopathy, resulting from myocarditis, is the most common cause of heart failure in young patients. We here show that interleukin (IL)-1 receptor type 1–deficient (IL-1R1−/−) mice are protected from development of autoimmune myocarditis after immunization with α-myosin-peptide(614–629)....

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Bibliographic Details
Main Authors: Eriksson, Urs, Kurrer, Michael O., Sonderegger, Ivo, Iezzi, Giandomenica, Tafuri, Anna, Hunziker, Lukas, Suzuki, Shinobu, Bachmaier, Kurt, Bingisser, Roland M., Penninger, Josef M., Kopf, Manfred
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193833/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193833/

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