Rapid Induction of Tumor-specific Type 1 T Helper Cells in Metastatic Melanoma Patients by Vaccination with Mature, Cryopreserved, Peptide-loaded Monocyte-derived Dendritic Cells

Rapid Induction of Tumor-specific Type 1 T Helper Cells in Metastatic Melanoma Patients by Vaccination with Mature, Cryopreserved, Peptide-loaded Monocyte-derived Dendritic Cells

There is consensus that an optimized cancer vaccine will have to induce not only CD8+ cytotoxic but also CD4+ T helper (Th) cells, particularly interferon (IFN)-γ–producing, type 1 Th cells. The induction of strong, ex vivo detectable type 1 Th cell responses has not been reported to date. We demons...

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Bibliographic Details
Main Authors: Schuler-Thurner, Beatrice, Schultz, Erwin S., Berger, Thomas G., Weinlich, Georg, Ebner, Susanne, Woerl, Petra, Bender, Armin, Feuerstein, Bernadette, Fritsch, Peter O., Romani, Nikolaus, Schuler, Gerold
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193752/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193752/

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