Link between Organ-specific Antigen Processing by 20S Proteasomes and CD8+ T Cell–mediated Autoimmunity

Link between Organ-specific Antigen Processing by 20S Proteasomes and CD8+ T Cell–mediated Autoimmunity

Adoptive transfer of cross-reactive HSP60-specific CD8+ T cells into immunodeficient mice causes autoimmune intestinal pathology restricted to the small intestine. We wondered whether local immunopathology induced by CD8+ T cells can be explained by tissue-specific differences in proteasome-mediated...

Full description

Bibliographic Details
Main Authors: Kuckelkorn, Ulrike, Ruppert, Thomas, Strehl, Britta, Jungblut, Peter R., Zimny-Arndt, Ursula, Lamer, Stephanie, Prinz, Immo, Drung, Ilse, Kloetzel, Peter-M., Kaufmann, Stefan H.E., Steinhoff, Ulrich
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193696/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193696/

Similar Items