Friend of GATA-1 Represses GATA-3–dependent Activity in CD4+ T Cells

The development of naive CD4+ T cells into a T helper (Th) 2 subset capable of producing interleukin (IL)-4, IL-5, and IL-13 involves a signal transducer and activator of transcription (Stat)6-dependent induction of GATA-3 expression, followed by Stat6-independent GATA-3 autoactivation. The friend o...

Full description

Bibliographic Details
Main Authors: Zhou, Meixia, Ouyang, Wenjun, Gong, Qian, Katz, Samuel G., White, J. Michael, Orkin, Stuart H., Murphy, Kenneth M.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193678/