The Multiple Immune-Evasion Genes of Murine Cytomegalovirus Are Not Redundant: m4 and m152 Inhibit Antigen Presentation in a Complementary and Cooperative Fashion
Both human cytomegaloviruses (HCMVs) and murine cytomegaloviruses (MCMVs) encode multiple genes that interfere with antigen presentation by major histocompatibility complex (MHC) class I, and thus protect infected targets from lysis by virus-specific cytotoxic T lymphocytes (CTLs). HCMV has been sho...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2001
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193484/ |