The Multiple Immune-Evasion Genes of Murine Cytomegalovirus Are Not Redundant: m4 and m152 Inhibit Antigen Presentation in a Complementary and Cooperative Fashion

Both human cytomegaloviruses (HCMVs) and murine cytomegaloviruses (MCMVs) encode multiple genes that interfere with antigen presentation by major histocompatibility complex (MHC) class I, and thus protect infected targets from lysis by virus-specific cytotoxic T lymphocytes (CTLs). HCMV has been sho...

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Bibliographic Details
Main Authors: Kavanagh, Daniel G., Gold, Marielle C., Wagner, Markus, Koszinowski, Ulrich H., Hill, Ann B.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193484/