Quantitative Regulation of Class Switch Recombination by Switch Region Transcription

The isotype specificity of immunoglobulin (Ig) class switching is regulated by a cytokine which induces transcription of a specific switch (S) region, giving rise to so-called germline transcripts. Although previous studies have demonstrated that germline transcription of an S region is required for...

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Bibliographic Details
Main Authors: Lee, Chung-Gi, Kinoshita, Kazuo, Arudchandran, Arulvathani, Cerritelli, Susana M., Crouch, Robert J., Honjo, Tasuku
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193461/