Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy

In human breast carcinomas, overexpression of the macrophage colony–stimulating factor (CSF-1) and its receptor (CSF-1R) correlates with poor prognosis. To establish if there is a causal relationship between CSF-1 and breast cancer progression, we crossed a transgenic mouse susceptible to mammary ca...

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Bibliographic Details
Main Authors: Lin, Elaine Y., Nguyen, Andrew V., Russell, Robert G., Pollard, Jeffrey W.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193412/