Legionella pneumophila Replication Vacuoles Mature into Acidic, Endocytic Organelles

After ingestion by macrophages, Legionella pneumophila inhibits acidification and maturation of its phagosome. After a 6–10-h lag period, the bacteria replicate for 10–14 h until macrophage lysis releases dozens of progeny. To examine whether the growth phase of intracellular L. pneumophila determin...

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Bibliographic Details
Main Authors: Sturgill-Koszycki, Sheila, Swanson, Michele S.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193360/