Homeostasis-Stimulated Proliferation Drives Naive T Cells to Differentiate Directly into Memory T Cells
The developmental requirements for immunological memory, a central feature of adaptive immune responses, is largely obscure. We show that as naive CD8 T cells undergo homeostasis-driven proliferation in lymphopenic mice in the absence of overt antigenic stimulation, they progressively acquire phenot...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193235/ |