Opposing Effects of Transmembrane and Soluble FAS Ligand Expression on Inflammation and Tumor Cell Survival
Fas ligand (FasL) has been shown to mediate both apoptotic and inflammatory reactions. To rigorously assess the physiological role of different forms of the FasL molecule with regard to these two distinct processes, we isolated stably transfected lymphoma cell lines that expressed either murine wild...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193164/ |