Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV-induced tumors express this foreign antigen. However, EBNA1 is invisible to CD8+ cytotoxic T lymphocytes because its Gly/Al...

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Bibliographic Details
Main Authors: Münz, Christian, Bickham, Kara L., Subklewe, Marion, Tsang, Ming L., Chahroudi, Ann, Kurilla, Michael G., Zhang, Dan, O'Donnell, Michael, Steinman, Ralph M.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193162/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193162/

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