Apoptotic Protease Activating Factor 1 (Apaf-1)–Independent Cell Death Suppression by Bcl-2

Apoptotic Protease Activating Factor 1 (Apaf-1)–Independent Cell Death Suppression by Bcl-2

Reportedly, antiapoptotic Bcl-2 family proteins suppress apoptosis by binding to and inhibiting members of the CED-4 family of caspase activators. To explore this question, we used embryonic stem (ES) cells in which one (−/+) or both (−/−) copies of the gene encoding apoptotic protease activating fa...

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Bibliographic Details
Main Authors: Haraguchi, Misako, Torii, Seiji, Matsuzawa, Shu-ichi, Xie, Zhihua, Kitada, Shinichi, Krajewski, Stanislaw, Yoshida, Hiroki, Mak, Tak W., Reed, John C.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193150/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193150/

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