Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex

Susceptibility to multiple sclerosis (MS) is associated with the human histocompatibility leukocyte antigen (HLA)-DR2 haplotype, suggesting that major histocompatibility complex class II–restricted presentation of central nervous system–derived antigens is important in the disease process. Antibodie...

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Bibliographic Details
Main Authors: Krogsgaard, Michelle, Wucherpfennig, Kai W., Canella, Barbara, Hansen, Bjarke E., Svejgaard, Arne, Pyrdol, Jason, Ditzel, Henrik, Raine, Cedric, Engberg, Jan, Fugger, Lars
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193136/