Evolution of Antigen-specific T Cell Receptors In Vivo: Preimmune and Antigen-driven Selection of Preferred Complementarity-determining Region 3 (CDR3) Motifs

Evolution of Antigen-specific T Cell Receptors In Vivo: Preimmune and Antigen-driven Selection of Preferred Complementarity-determining Region 3 (CDR3) Motifs

Antigen (Ag)-driven selection of helper T cells (Th) in normal animals has been difficult to study and remains poorly understood. Using the major histocompatibility complex class II– restricted murine response to pigeon cytochrome c (PCC), we provide evidence for both preimmune and Ag-driven selecti...

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Bibliographic Details
Main Authors: McHeyzer-Williams, Louise J., Panus, Joanne Fanelli, Mikszta, John A., McHeyzer-Williams, Michael G.
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193074/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193074/

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