Immunoglobulin-binding Sites of Human FcαRI (CD89) and Bovine Fcγ2R Are Located in their Membrane-distal Extracellular Domains

To localize the immunoglobulin (Ig)-binding regions of the human Fcα receptor (FcαRI, CD89) and the bovine Fcγ2 receptor (bFcγ2R), chimeric receptors were generated by exchanging comparable regions between these two proteins. FcαRI and bFcγ2R are highly homologous and are more closely related to eac...

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Bibliographic Details
Main Authors: Craig Morton, H., van Zandbergen, Ger, van Kooten, Cees, Howard, Chris J., van de Winkel, Jan G. J., Brandtzaeg, Per
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193073/