Defective Interleukin (IL)-18–mediated Natural Killer and T Helper Cell Type 1 Responses in IL-1 Receptor–associated Kinase (IRAK)-deficient Mice
Interleukin (IL)-18 is functionally similar to IL-12 in mediating T helper cell type 1 (Th1) response and natural killer (NK) cell activity but is related to IL-1 in protein structure and signaling, including recruitment of IL-1 receptor–associated kinase (IRAK) to the receptor and activation of c-J...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1999
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193007/ |