The Reversible Modification Regulates the Membrane-Binding State of Apg8/Aut7 Essential for Autophagy and the Cytoplasm to Vacuole Targeting Pathway
Autophagy and the Cvt pathway are examples of nonclassical vesicular transport from the cytoplasm to the vacuole via double-membrane vesicles. Apg8/Aut7, which plays an important role in the formation of such vesicles, tends to bind to membranes in spite of its hydrophilic nature. We show here that...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192639/ |