IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosity
Contrary to expectations based on in vitro experiments, we previously found that pancreatic IL-10 did not inhibit autoimmune diabetes but accelerated it in an MHC-dependent manner. Therefore, the ability of IL- 10 to overcome the absence of all non-MHC diabetes susceptibility (Idd) alleles was studi...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1996
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192620/ |