The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice
The role of cell-mediated cytotoxicity in the complex pathophysiology of graft-versus-host disease (GVHD) has remained poorly defined for several decades. We transplanted T cells from Fas-ligand (FasL)- defective and perforin-deficient mutant donor mice into lethally irradiated MHC-matched allogenei...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1996
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192602/ |