Phosphorylation-Dependent Regulation of Ryanodine Receptors: A Novel Role for Leucine/Isoleucine Zippers

Ryanodine receptors (RyRs), intracellular calcium release channels required for cardiac and skeletal muscle contraction, are macromolecular complexes that include kinases and phosphatases. Phosphorylation/dephosphorylation plays a key role in regulating the function of many ion channels, including R...

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Bibliographic Details
Main Authors: Marx, Steven O., Reiken, Steven, Hisamatsu, Yuji, Gaburjakova, Marta, Gaburjakova, Jana, Yang, Yi-Ming, Rosemblit, Nora, Marks, Andrew R.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192391/