A Link between the Synthesis of Nucleoporins and the Biogenesis of the Nuclear Envelope

The nuclear pore complex (NPC) is a multicomponent structure containing a subset of proteins that bind nuclear transport factors or karyopherins and mediate their movement across the nuclear envelope. By altering the expression of a single nucleoporin gene, NUP53, we showed that the overproduction o...

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Bibliographic Details
Main Authors: Marelli, Marcello, Lusk, C. Patrick, Chan, Honey, Aitchison, John D., Wozniak, Richard W.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192385/